QUASI-EXPERIMENTAL DESIGN FOR EXTERNAL CONTROL ARM STUDIES ALONGSIDE SINGLE ARM TRIALS FOR REGULATORY PURPOSES

Quasi-experimental design for external control arm studies alongside single arm trials for regulatory purposes

To accelerate new drug, biologic, and medical device development and to improve efficiency of delivery of the latest breakthroughs of innovative, life-saving treatments to millions of patients, single-arm trial (SAT) applications of rare diseases or conditions supplemented by their TV Stick Set external control arm (ECA) evidence for regulatory app

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Hardware Accelerated Sequence Alignment with Traceback

Biological sequence alignment is an essential tool used in molecular biology and biomedical applications.The growing volume of genetic data and the complexity of sequence alignment present a challenge in obtaining alignment results in a timely manner.Known methods to accelerate alignment on reconfigurable hardware only address sequence comparison,

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